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MedChemExpress
dtag 7 Dtag 7, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/dtag+7/FKBP12+PROTAC+dTAG-7/pmc12396338-167-9-10 Average 93 stars, based on 1 article reviews
dtag 7 - by Bioz Stars,
2026-09
93/100 stars
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Tocris
dtag7 ligand tocris 6912 t4 pnk 3 ![]() Dtag7 Ligand Tocris 6912 T4 Pnk 3, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/dtag+7/dTAG-7/pm38810649-230-120-122 Average 93 stars, based on 1 article reviews
dtag7 ligand tocris 6912 t4 pnk 3 - by Bioz Stars,
2026-09
93/100 stars
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Tocris
dtag 7 ![]() Dtag 7, supplied by Tocris, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/dtag+7/dTAG-7/pmc10162582-414-45-46 Average 96 stars, based on 1 article reviews
dtag 7 - by Bioz Stars,
2026-09
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FKBP12 PROTAC dTAG-7 is a bifunctional PROTAC® degrader inducing the selective degradation of FKBP12F36V fusion proteins and BET BRD4, consisting of a ligand selective for F36V single-point mutated FKBP12 conjugated to a cereblon ligand by
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FKBP12 PROTAC dTAG-7 (dTAG-7) is a heterobifunctional degrader. FKBP12 PROTAC dTAG-7 (dTAG-7) is a degrader of FKBP12 F36V with expression of FKBP12 F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-7 (dTAG-7) also is
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Image Search Results
Journal: Molecular cell
Article Title: FACT maintains chromatin architecture and thereby stimulates RNA polymerase II pausing during transcription in vivo.
doi: 10.1016/j.molcel.2024.05.003
Figure Lengend Snippet: Figure 2. A minor role for FACT in higher-order chromatin organization (A) Localized contact matrices (50 bp resolution) derived from Tiled-MCC ligation junctions of the MYC and GATA2 loci in cells treated with solvent only (control, top) and dTAG7 ligand (dSSRP1, bottom). Gene annotation, DNase I hypersensitive sites (DHSs), and ChIP-seq tracks of H3K27ac and CTCF for wild-type K562 cells are shown at the bottom.
Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies anti-RNA Pol II CTD (total) Diagenode C15200004, RRID;AB_2728744 anti-HA Roche 11867423001; RRID:AB_390918 anti-alpha-tubulin SCBT sc-69971; RRID:AB_2210059 anti-H3 Abcam ab21054; RRID:AB_880437 anti-U1-snRNP70 SCBT sc-390899; RRID:AB_2801569 anti-SPT16 BioLegend 607008; RRID:AB_2721598 anti-SSRP1 BioLegend 609710; RRID:AB_2650944 Rpb1 NTD antibody Cell Signaling Technology 14958; RRID:AB_2687876 Th1L (NELF C/D) antibody Cell Signaling Technology 12265; RRID:AB_2797862 Spike-in Antibody Active Motif 61686; RRID:AB_2737370 Bacterial and virus strains BL21 (RIL) DE3 Agilent 230245 XL1 Blue Agilent 200249 Hi5 cells Expression Systems 94-002F Sf9 cells Thermo Fischer 12659017 Sf21 cells Expression Systems 94-003S ESF 921 Expression Systems 96-001-01 Biological samples Sus scrofa thymus Locally sourced N/A Chemicals, peptides, and recombinant proteins EZ-link HPDP-biotin Pierce 21341 DMSO Sigma-Aldrich D8418-50ML 4-thiouridne Carbosynth NT06186 Empigen Sigma-Aldrich 30326-250ML
Techniques: Derivative Assay, Ligation, Solvent, Control, ChIP-sequencing